OPRA: Therapeutics & patient care
Therapeutics and patient care is the largest OPRA domain — roughly 45% of the exam — so it's where focused practice pays off most.
High-yield areas
- Cardiovascular (hypertension, heart failure, lipids, anticoagulation)
- Respiratory (asthma & COPD), endocrine (diabetes, thyroid)
- Infectious diseases & antimicrobial choice
- Pain, CNS/mental health, GI, renal and women's health
How to study it
Pair each condition's Crash Course concept with a set of scenario questions, then let spaced repetition resurface what you miss. Because it's the biggest domain, give it the most time.
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Create a free account and practise 50 questions, 5 Crash Course modules and the full Calculations Lab — no payment needed.
Start freeFrequently asked questions
How much of OPRA is therapeutics?
Approximately 45% — the largest single domain, worth more marks than the other four combined.
What topics sit in the therapeutics and patient care domain?
Cardiovascular, respiratory, endocrine, gastrointestinal, infectious disease, mental health, pain, oncology, renal and women's health therapeutics — alongside counselling, medication safety and quality use of medicines.
Should I study therapeutics first?
For most candidates, yes. At roughly 45% of the paper it carries the most marks, so early gains here move your overall score further than the same effort spent on a 10% domain.
Free study guides
In-depth, free to read — no account needed.
- Hypertension for OPRA: Diagnosis, Treatment, Counselling and MCQs →
- Type 2 Diabetes Management for OPRA: Drug Choice, Targets, Sick-Day Rules and MCQs →
- Warfarin and Anticoagulation for OPRA: Mechanism, INR, Interactions and MCQs →
- Asthma and COPD for OPRA: Current Guidelines, Inhalers and MCQs →
- Antimicrobial Selection for OPRA: Empirical Therapy, Allergy and MCQs →
- Immunisation for OPRA: Vaccines, Schedule Principles and MCQs →
- Heart Failure for OPRA: Four-Pillar Therapy, HFrEF vs HFpEF and MCQs →
- Paediatric Dosing Calculations for OPRA: mg/kg, Dose Caps and MCQs →
- Antidepressants for OPRA: SSRIs, Serotonin Toxicity and MCQs →
- Thyroid Disorders for OPRA: Levothyroxine, Carbimazole and MCQs →
- Dyslipidaemia and Statins for OPRA: Muscle Effects, Interactions and MCQs →